Abstract
This chapter discusses development of a needle-type biosensor for the traditional Chinese medical acupuncture therapy and the assay of dopamine. The traditional Chinese medical acupuncture therapy is widely spread over the world now. The Meridian theory, as the theoretical basis for the traditional Chinese medicine, has directed the manipulation for a long time. To monitor the molecular event occurring in meridian and acupoint, a novel biosensor which is a combination of the traditional Chinese medical sensing needle and tissue-based carbon paste microelectrode has been developed. The biosensor, which is both an actuator and a sensor, can be employed to the acupuncture therapy as well as detection of neurotransmitter-dopamine (DA). The construction of biosensor a stainless steel hollow sensing needle with inner wall insulated, and a small hole on its lower part is filled with spinach tissue-based carbon paste which is electrically connected by inserting a copper wire. The detection limit reaches 10−7 mol/L and the life time one month. In vitro characterization experiments have shown the sensor's performance to be acceptable. The biosensor is used in the initial study of neurotransmitter DA in acupoint.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
