4‐(4‐Propylpiperazine‐1‐yl)butane‐1‐sulfonic acid‐modified silica‐coated magnetic nanoparticles: A novel and recyclable catalyst for the synthesis of 5‐arylidinebarbituric acids and pyrano[2,3‐d]pyrimidinedione derivatives in aqueous media

Abstract

A mild, simple and efficient procedure for the preparation of barbituric acid and pyrano[2,3‐d]pyrimidine derivatives in aqueous media is described using 4‐(4‐propylpiperazine‐1‐yl)butane‐1‐sulfonic acid‐modified silica‐coated magnetic nanoparticles as a novel and reusable catalyst. The catalyst was easily isolated from the reaction mixture by magnetic decantation using an external magnet and reused at least eight times without significant degradation in activity.