Abstract

Background Viability assessment is a key aspect in the management of ischaemic heart disease (IHD). Hypothesis: native T1 and T2 mapping can assess myocardial viability without the use of gadolinium. Methods 30 patients with known MI (>5yrs from MI) and 20 normal healthy controls underwent conventional 1.5T CMR to assess LV function and the presence and extent of myocardial infarction (scar transmurality) using a scale of 0–4 for the 16 AHA segment (0=no scar, 1=1–24%, 2=25–49%, 3=50–74% and 4 ≥75% scar thickness). Segments with Results 800 myocardial segments were analysed (320-healthy controls, 480-MI patients). The mean segmental T1 and T2 values for scar transmurality grade 0–4 were 1031±31 ms, 1070±33 ms, 1103±32 ms, 1164±58 ms, 1206±118 ms (p Conclusions Native T1 mapping can differentiate between normal, viable, and non-viable myocardium with distinctive T1 profiles in chronic MI without the need for gadolinium.

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