Abstract

A new friedelane type triterpene, 3-oxo-11β-hydroxyfriedelane, named as monospermol, was isolated from the roots of Celastrus monospermus Roxb.(Celastraceae) along with seven known compounds friedelin, 3,12-dioxofriedelane, 3-oxo-28-hydroxyfriedelane, 3-oxo-12α-hydroxyfriedelane, β-sitosterol, pristimerin and celastrol. Structural formula and the stereochemistry of the new friedelane type triterpene 1 were established through 1H NMR and 13C NMR spectral data including 2D experiments (HMBC, HSQC, 1H-1H COSY and NOESY) and high resolution mass spectrometry.

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