Abstract

Recent studies have shown that the microbiota during the early years of an individual’s life is affected by the mode of release during childbirth, differing between caesarean section and newborns born vaginally. Here we reported the selection of nomadic lactobacilli for the development of a multi-strain probiotic gel to promote lactobacilli-dominated vaginal microbiota in pregnant women and to establish a proper eubiosis in the new-born. Lactobacilli, mainly isolated from food sources, were screened for functional characteristics and the capability to inhibit Streptococcus agalactiae and Candida albicans, which may lead to adverse pregnancy-related outcomes.

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