Abstract
Background: Contributing factors to digital myxoid cyst (DMC) development remain unclear, and a history of osteoarthritis (OA) is often attributed as a key risk factor. Our goal was to identify characteristics associated with development of DMCs. Methods: Thirty-six patients diagnosed with DMCs at Weill Cornell Dermatology from 06/01/2016-12/31/2020 were identified and charts were reviewed. Statistical analysis used means and 95% confidence intervals (CI). Results: The majority of patients were female (69.4%, CI: [51.9%, 83.7%]) and White (73.1%, CI: [52.2%, 88.4%]; vs 19.2% Black, CI: [6.5%, 39.4%]; vs 2.8% Asian, CI: [0.1%, 19.6%]). Average age was 63.8 years (CI: [59.4, 68.1]), and 94.4% were over age 50. Cysts were predominantly on fingers (91.7% vs 8.3% on toes), and 97.2% were singular. Cysts were more common on the right hand (64.7%, CI: [46.5%, 80.3%]) and middle finger (35.3% vs 5.9% on pinky). Most patients had no digit trauma (86.1%, CI: [70.5%, 95.3%]). Notably, only 38.9% had a prior history of OA. Only 8.3% had finger joint pain, but 30.6% reported nail pain. For patients with hand x-rays (n = 21), 80.9% (CI: [58.1%, 94.6%]) had OA in the affected hand. Only 57.1% (CI: [34.0%, 78.2%]) had OA at nearest DIP joint. Conclusion: Female gender, White race, age older than 50, and singular, right-handed lesions were associated with DMC diagnosis. While most x-rays showed OA, the majority of patients had no joint pain or OA history; therefore, diagnosis should still be suspected regardless of an absence of OA history or other OA symptoms.
Published Version
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