33. Association between QT Dispersion and Left Ventricular Hypertrophy in Hypertensive Heart Disease Patients

Abstract

Background: The variation in QT length reflects regional repolarization differences in the heart. An Increased in QT dispersion is associated with an increased left ventricular mass index in hypertensive individuals. Objective: The aim of this study was to investigate association between QT dispersion and left ventricular hypertrophy (LVH) in hypertensive heart disease (HHD) individuals. Method: This study was a-single centre, retrospective study, included 47 patients with hypertension who had visited the cardiology clinic. Electrocardiography (EKG) and trans-thoracal echocardiography (TTE) were performed. Patients were divided into LVH group (27) and control group (20) based on TTE findings. Patients with valvular abnormalities, myocardial infarction, LV dysfunction, pericardial disease, arrhythmia related, and pulmonary disease were excluded from this study. Results: LVH was diagnosed in 31 (56%) of the patients by 2D echocardiography. The QT interval maximum was higher at 414.00 ± 59.87, than 396.19 ± 37.75 in the control group. Corrected QT (QTc) maximum in HHD group also higher at 448.08 ± 54.83 compared to control group in 421.67 ± 35.61. QT minimum and QTc minimum both are higher in HHD group at 350.40 ± 53.27 and 378.32 ± 43.00 respectively than in controlled group, at 339.05 ± 43.12 and 361.29 ± 45.26. There was no significant association in QT dispersion (p = 0.582) and QTc dispersion (p = 0.265) between HHD group and controlled group. Conclusion: The QT dispersion trend was narrowly higher in hypertensive patient with LVH in HHD group than the controlled group but it was statistically insignificant.