Abstract
In the title molecule, C16H15FN4O, the dihedral angle between the fluoro-substituted benzene ring and the pyrimidinone ring is 52.34 (7)°, while the dihedral angle between the fused benzene ring and the pyrimidinone ring is 3.30 (6)°. An intramolecular N—H⋯N hydrogen bond may, in part, influence the conformation of the molecule. In the crystal structure, intermolecular N—H⋯N hydrogen bonds and weak C—H⋯π(arene) interactions link pairs of molecules into centrosymmetric dimers.
Highlights
Data collectionFaculty of Chemistry and Life Science, Xianning University, Xianning 437100, People’s Republic of China
In the title molecule, C16H15FN4O, the dihedral angle between the fluoro-substituted benzene ring and the pyrimidinone ring is 52.34 (7), while the dihedral angle between the fused benzene ring and the pyrimidinone ring is 3.30 (6)
In connection with our ongoing heterocyclic synthesis and drug discovery project (Yang et al, 2008), we have focused our research on the synthesis of quinazolinones and pyrazolo pyrimidinones
Summary
Faculty of Chemistry and Life Science, Xianning University, Xianning 437100, People’s Republic of China. R factor = 0.038; wR factor = 0.111; data-to-parameter ratio = 13.0. C16H15FN4O, the dihedral angle between the fluoro-substituted benzene ring and the pyrimidinone ring is 52.34 (7) , while the dihedral angle between the fused benzene ring and the pyrimidinone ring is 3.30 (6). An intramolecular N—H N hydrogen bond may, in part, influence the conformation of the molecule. Intermolecular N—H N hydrogen bonds and weak C—H (arene) interactions link pairs of molecules into centrosymmetric dimers
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