329 Regional Cerebral Oxygen Saturation During Neonatal Transition - Comparison of Vaginal Delivery Vs. Cesarian Section

Abstract

Aim: The aim of the study was to investigate whether regional cerebral oxygen saturation (rSO2brain) shows significant differences in infants delivered by cesarian section (CS) compared to vaginal delivery (VD). Methods: Prospective observational study rSO2brain and preductal arterial oxygen saturation (SpO2) were measured during the first 15 minutes of life. Only healthy term infants with uncomplicated adaptation were included. Fractional tissue oxygen extraction (FTOE) was calculated. Data are presented as mean. A linear mixed model with a fixed effect for time and a first order autoregressive covariance structure was used for calculation of significant differences. Results: Between October 2009 and April 2010, 63 infants delivered by VD, and 29 infants delivered by elective CS were included into the study. SpO2 was 66% (CS)/73% (VD) at minute 2, 81%(CS)/89%(VD) at minute 5, 93%(CS)/95%(VD) at minute 10, and 95%(CS)/97%(VD) at minute 15. There was a significant difference in SpO2 data between VD and CS until minute 6, showing higher values in VD group. rSO2brain was 34%(CS)/39%(VD) at minute 2, 67%(CS)/69%(VD) at minute 5, 80%(CS)/77%(VD) at minute 10, and 80%(CS)/75%(VD) at minute 15. rSO2brain did not show any significant difference between CS and VD. FTOE was 0.49(CS)/0.46(VD) at minute 2, 0.19(CS)/0.22(VD) at minute 5, 0.13(CS)/0.19(VD) at minute 10, and 0.16(CS)/0.22(VD) at minute 15. FTOE did not show significant differences between CS and VD until minute 11, afterwards FTOE in VD group was higher. Conclusion: rSO2brain was not constricted in CS group compared to VD group, which is in contrast to SpO2 behaviour.