Abstract
Touch dome, a specialized epidermal structure comprised from mechanosensory Merkel cell-neurite complex, has been known to change their numbers in the spontaneous hair cycle in mice. At the anagen phase, the number of Merkel cells are dramatically reduced with the loss of terminal neurites in touch dome afferents, indicating neuronal plasticity in healthy skin during hair-follicle regeneration. In this study, we focused on the role of Merkel cell-neurite complex in hair growth on the basis of the reports that the mechanical stimulation of human scalp by a massage improves hair thickness.
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