324. CLINICAL OUTCOME OF CURATIVE SURGERY AND DEFINITIVE CHEMORADIOTHERAPY FOR PATIENTS WITH RESECTABLE CERVICAL ESOPHAGEAL CANCER

Abstract

Abstract Esophagectomy and definitive chemoradiotherapy are standard initial treatment modality for resectable cervical esophageal cancer. We compared the treatment results of both treatment methods and examined treatment strategies for resectable cervical esophageal cancer. Patients who were treated for resectable cervical esophageal cancer at our hospital from January 2003 to March 2017 were divided into surgery group and chemoradiation therapy group (CRT group) for the initial treatment. The treatment results were compared retrospectively. Of all 51 patients, 20 patients received surgery and 31 received CRT. In surgery group, 16 cases lost their laryngeal function by surgery. Recurrence was observed in 7 cases, of which only 1 case was local. In CRT group, 26 cases (83.9%) achieved complete response, of which 13 cases relapsed. 5-year laryngeal-preserving survival rate was 56.2% in CRT group, and 72.3% for non-stenotic patients. There was no significant difference in 5-year survival rate between two groups (surgery, 62.2%; CRT, 66.1; p = 0.648). In stenotic cases, 5-year survival rate was better in surgery group (surgery, 75 0.0%; CRT, 25.0%; p = 0.033). The local control of the primary lesion and the prognosis in the stenotic cases were better in the surgery group. On the other hand, the 5-year laryngeal-preserving survival rate of the CRT group was high in non-stenotic cases. These results can be an important factor in choosing initial treatment for resectable cervical esophageal cancer.