32080 Diffuse annular elastolytic giant cell granuloma with a rapid response to hydroxychloroquine

Abstract

An 83-year-old man with a history of monoclonal gammopathy presented with a 3-month history of diffuse annular erythematous to violaceous plaques with a prominent border starting on his upper extremities and face and then progressing to involve his back, upper chest, and anterior thighs. He admitted to intense pruritus and some pain of these lesions. He denied fever, chills, night sweats, or any new medications. A punch biopsy from the newest plaque on the right anterior thigh demonstrated a granulomatous histiocytic infiltrate composed of multinucleated giant cells exhibiting elastophagocytosis.