31ièmes Journées Franco-Belges de Pharmacochimie: Meeting Report.

Raphaël Frédérick,Lionel Pochet,Pascal De Tullio,François Dufrasne

doi:10.3390/ph10040094

Abstract

The “Journées Franco-Belges de Pharmacochimie” is a recognized two-day annual meeting on Medicinal Chemistry that is renowned for the advanced science presented, conviviality, and outstanding opportunities for senior and young scientists to exchange knowledge. s of plenary lectures, oral communications, and posters presented during the meeting are collected in this report.

Highlights

The “Journées Franco-Belges de Pharmacochimie” (JFB) is a widely recognized annual meeting on Medicinal Chemistry. This two-day symposium aims to promote exchanges between medicinal chemists, mainly from France and Belgium. It is renowned for the advanced science presented, conviviality, and outstanding opportunities for senior and young scientists to exchange knowledge
This approach will be illustrated using one target enzyme from the methyl erythritol phosphate pathway. This pathway provides a rich source of drug targets, given that pathogens such as Mycobacterium tuberculosis and Plasmodium falciparum use this pathway for the biosynthesis of the essential isoprenoid precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), while humans exclusively utilise the alternative mevalonate pathway
To facilitate the development of potent and selective inhibitors of d-xylulose-5-phosphate synthase (DXS), we have explored ligand

Summary

Aim and Scope of the Meeting

The “Journées Franco-Belges de Pharmacochimie” (JFB) is a widely recognized annual meeting on Medicinal Chemistry This two-day symposium aims to promote exchanges between medicinal chemists, mainly from France and Belgium. It is renowned for the advanced science presented, conviviality, and outstanding opportunities for senior and young scientists to exchange knowledge. The themes discussed during the meeting were those generally encountered by medicinal chemists: organic synthesis, bioinformatics and computer-aided drug design, pharmacological tests and molecular biology. This year, the official language for the lectures was English

Plenary Lecture

Oral Communications

Conclusions