Abstract
The “Journées Franco-Belges de Pharmacochimie” is a recognized two-day annual meeting on Medicinal Chemistry that is renowned for the advanced science presented, conviviality, and outstanding opportunities for senior and young scientists to exchange knowledge. s of plenary lectures, oral communications, and posters presented during the meeting are collected in this report.
Highlights
The “Journées Franco-Belges de Pharmacochimie” is a recognized two-day annual meeting on Medicinal Chemistry that is renowned for the advanced science presented, conviviality, and outstanding opportunities for senior and young scientists to exchange knowledge
We investigated the importance of the 2,5-dichlorophenyl moiety and it appeared that it is needed for the FXIIa inhibition
New antimalarial drugs are needed and this is why our team is involved in the design and synthesis of new antimalarial compounds
Summary
Coumarin derivatives have been previously described as small-molecular-weight inhibitors of. The aim of the present work is the identification and characterization of ligands for the regulatory domain of human enzymes DNMT3A and DNMT3B, the domain PWWP. The aim of this project is to identify and develop inhibitors of human enzymes hIDO and hTDO. Our aim was to design a multi target-directed ligand (MTDL) gathering two properties: acetylcholinesterase (AChE). The aim of this project is to transfer usual reactions of indole chemistry to continuous flow process
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