304. Disturbed sleep is associated with worse health outcomes after spine surgery

Abstract

BACKGROUND CONTEXT Sleep hygiene is an important and essential component of wellbeing; however, little is known regarding the association between sleep disturbance and health-related quality of life (HRQL) in patients undergoing spine surgery. PURPOSE The purpose of this study is determine the association between sleep disturbance and other HRQL measures in patients undergoing spine surgery. We hypothesize that sleep disturbance is significantly correlated with HRQL in patients undergoing surgical treatment of cervical and lumbar spinal disorders, and that patients with preoperative sleep disturbance have significant improvement in sleep postoperatively. STUDY DESIGN/SETTING Prospective cohort study. PATIENT SAMPLE A total of 583 spine surgery patients (cervical, lumbar and spinal deformity) with postoperative followup PROMIS scores. OUTCOME MEASURES Improvement in HRQL domains. Including PROMIS pain, fatigue, anxiety, depression, physical function, social satisfaction, Short Form -12 (SF12) and ODI scores. METHODS Spine surgery patients completed the Oswestry Disability Index (ODI), Short Form-12 (SF12) mental (MCS) health and PROMIS sleep, fatigue, physical function, anxiety, depression and social satisfaction domains at preop and 6-week postoperative visit. Pearson correlation was used to assess for correlation between sleep and HRQL measures, significance was set at p RESULTS In 583 patients (mean age 60 years, 55% female) sleep disturbance was prevalent in 177 (30%) and 94 (16%) patients preoperatively and 6 weeks following surgery, respectively. Sleep disturbance was most significantly correlated with MCS and ODI disability scores (r= - 0.485 and 0.405, respectively), p CONCLUSIONS Preoperative sleep disturbance in patients undergoing surgical treatment of spinal disorders is significantly correlated with several established HRQL measurement instruments. Moreover, improvement in sleep disturbance is also a significant predictor of improvement in postop pain, fatigue, depression, anxiety, physical function, social satisfaction and ODI scores. FDA DEVICE/DRUG STATUS This abstract does not discuss or include any applicable devices or drugs.