Abstract

Atopic dermatitis (AD) and psoriasis are common, chronic inflammatory skin diseases that carry a significant comorbidity burden, with patient populations showing increased prevalence of a range of conditions, including cardio-metabolic, respiratory, and psychiatric disorders. Predictive biomarkers for comorbidity development can help direct at-risk patients towards preventative lifestyle and/or clinical interventions which will improve patient outcomes and reduce overall healthcare burden. We identified 92 established or hypothesised AD and psoriasis comorbidities (73 common to both diseases) with prevalence >2% in UK Biobank (UKB).

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