300 Clinical assessment of low level microcurrent of short duration in enhancing allantoin penetration and improving the appearance of skin cellulite, radiance, texture, and firmness

Abstract

Low level DC microcurrent is used to enable electrically conductive drug delivery in skin wounds and ulcerations. However, it is not clear from the literature whether very low level DC current of short-term duration can improve the delivery of active ingredients contributing to the improvement of skin appearance. We conducted a 12-week study in 30 females using a non-invasive negative DC microcurrent device to deliver allantoin from a topical serum followed by a moisturizer. Consistent areas on the upper thigh and upper arm were evaluated visually for improvement in skin cellulite, radiance, texture, and firmness.