Abstract

SynopsisThe aim of this study was to determine how worthwhile it would be to combine a newly developed topical slimming product with customized dietary habits not based on calorie restriction, so as to improve the cellulite appearance of the skin. At the beginning of the study, a nutritionist recorded the dietary habits of each participant and gave recommendations to each of them according to their food consumption. The chosen methodology was a right/left comparison, one thigh and hip being treated with the new topical slimming product and the other one left untreated to serve as a random control. Objective evaluations were performed by blind assessors. Control of food intake improved the cellulite score after 4 weeks when compared with the base value, but this reduction was significantly greater and earlier on the treated side than on the untreated side, indicating an objective additional benefit derived from the new slimming cream. This result corroborated the slimming effect assessed by measurement in centimetres of the circumference of the upper thighs and the reconstructed volume of the thigh between two fixed horizontal slices. Furthermore, skin tonicity, a major component of cellulite visibility, was also significantly improved on the treated side after only 2 weeks.This new topical cream thus enhances the benefit of a dietetic control for the treatment of the visible aspect of cellulite on the skin.RésuméCette étude avait pour objectif d’étudier l'intérêt éventuel d'associer une nouvelle crème amincissante à des conseils nutritionnels personnalisés, non basés sur la restriction calorique mais sur un meilleur équilibre alimentaire afin d'améliorer l'aspect cellulitique de la peau. Au début de l’étude un médecin nutritionniste a enregistré les habitudes alimentaires de chaque sujet et a donné des recommandations à chacun en fonction de leur consommation alimentaire. La méthodologie contrôlée en hémi corps, gauche/droite a été choisie, une cuisse, une fesse ayant été traités par le produit à l’étude, l'autre partie du corps étant restée sans traitement selon la randomisation. Les évaluations objectives ont été réalisées par des investigateurs en aveugle. Le contrôle des aliments a permis une réduction du score de cellulite après 4 semaines mais cette réduction est statistiquement plus importante et plus rapide du côté traité avec le produit topique que du côté non traité, ce qui correspond à un effet additionnel objectivé du produit topique. Ce résultat est conforté par l'effet amincissant évalué par la mesure centimétrique de la circonférence de la partie supérieure de la cuisse et l’évolution du volume reconstruit de la cuisse entre deux niveaux. De plus la tonicité de la peau, composante importante de la visibilité de la cellulite, est améliorée significativement dès 2 semaines du coté traité;Cette nouvelle crème apporte donc un bénéfice complémentaire au contrôle diététique pour le traitement de la cellulite.

Highlights

  • Cellulite is a very frequent and complex condition that affects 85% of post-puberty female subjects [1]

  • Good diet and physical condition do not uniformly prevent the development of cellulite [8], and the effect of caloric restriction on cellulite appearance is still a matter of debate. It has been established for a long time that weight loss is rarely followed by cellulite reduction, and one recent study [9] has provided information on the great variability of responses after weight loss programmes

  • Whereas it shows some positive effect for the group with a large excess of body mass and a relatively high cellulite severity score at a 2011 The Authors

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Summary

Introduction

Cellulite is a very frequent and complex condition that affects 85% of post-puberty female subjects [1]. Even though its etiopathogenesis is not yet fully understood, many authors agree that cellulite has multifactorial – structural, genetic and endocrinological – causes It results from a complex series of inflammatory events involving both the subcutaneous fatty tissues and the dermis [1]. Good diet and physical condition do not uniformly prevent the development of cellulite [8], and the effect of caloric restriction on cellulite appearance is still a matter of debate It has been established for a long time that weight loss is rarely followed by cellulite reduction, and one recent study [9] has provided information on the great variability of responses after weight loss programmes. Whereas it shows some positive effect for the group with a large excess of body mass and a relatively high cellulite severity score at a 2011 The Authors

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