30. DNA prevalence of hepatitis B virus infection in the suspected population of Indian regions

Abstract

Background and Aims: Diagnosis of infection is the major aspects in HBV related symptoms, to provide accurate and timely treatment for infected patients. Objectives: To identify prevalence the present study was carried out to diagnose the HBV infection in DNA level with viral load in the suspected population in north, east, west and south Indian regions. Methods: A total of 515 suspected subjects from different regions; north (n = 277), east (n = 210), west (n = 16) and south (n = 12) of ages between 06 and 75 years (mean 35.90 years, standard deviation ± 14.14 years) included in this study. Results: HBV DNA was identified in a total of 360/515 (69.90%) suspected subjects; 269 (74.72%) male and 91 (25.27%) female. The level for viral load of HBV DNA ranged from 10.5 to >2 × 107 IU/ml in the samples used (median 461 IU/ml). The demographic data evaluation on the comparison of viral infection state between the regions and genders exhibited no significant correlation (P > 0.05). However, HBV DNA viral load difference among female indicated decreased proportion in the east regions (P = 0.01). There was no significant difference of viral load occurred between the genders in study population (P > 0.05). Conclusions: The results of this study show that HBV DNA prevalence among different regions and population is important to identify patient's diagnosis condition and prevention strategies in respective regions. To control the spread of infection among Indians are encouraged with diagnosis procedure in DNA level. Moreover, knowledge towards HBV infection risk and their roots are able to prevent virus transmission among Indian population. The authors have none to declare.