Abstract

In this chapter, the batch spintube and ultracentrifuge have been presented. The ultracentrifuge, capable of a million times gravity, has different operating modes that facilitate the measurement of sedimentation velocity and molecular weight and the separation of small cells and cellular organelles. Also, the versatile centrifugal filter that combines sedimentation, filtration, and chromatography carried out with different functional modules has been presented. Each process can be enhanced by the centrifugal field, including the chromatography process. In addition, a semibatch tubular centrifuge, capable of 20,000g, is discussed with either manual or automatic cake discharge. The traditional tubular uses a high length-to-diameter ratio, which requires manual cake removal, whereas the more modern tubular, which takes advantage of the solid-basket centrifuge design and has a length-to-diameter ratio of order up to 3, is designed with automatic cake discharge and more space for solid storage, and consequently it can take on feed with higher solids concentration.

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