Abstract

To investigate the relationship between the timing of thoracic endovascular aortic repair (TEVAR) and the development of stent graft–induced new entry (SINE) in chronic aortic dissection (CAD). This study enrolled 69 patients who underwent TEVAR for CAD since January 2006 through December 2017 and were followed up for at least 6 months. Their medical records were retrospectively reviewed. The patients were stratified by the timing of TEVAR into the early group (within 6 months from the onset of aortic dissection) and the late one (more than 6 months after the onset). The incidence of SINE and the interval between TEVAR and the development of SINE were compared between these groups. During the follow-up period, SINE occurred in 12% (3/26) in the early group, while 35% (15/43) in the late group (P = 0.029). The interval between TEVAR and the development of SINE was significantly longer in the late group than the early one (P = 0.002). According to the multivariate analysis, the late group (hazard ratio, 3.667; 95% confidence interval, 1.037–12.968, P = 0.044) and the distal oversizing ratio (hazard ratio, 1.492; 95% confidence interval, 1.071–2.080, P = 0.018) were the independent predictors of the development of SINE. SINE is not a rare complication following TEVAR for CAD. TEVAR should be performed in the early period to prevent SINE. Close and lifetime follow-up is mandatory for patients who undergo TEVAR more than 6 months after the onset.

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