3,5-Bis(4-pyridyl)-1,2,4-oxadiazole: An Unsymmetric Bidentate Ligand, Polymeric Silver Complex and Antimicrobial Activity Study

Abstract

1,2,4-Oxadiazole based unsymmetric bidentate ligand, 3,5-bis-(4-pyridyl)-1,2,4-oxadiazole has been employed for complexation with silver nitrate; this ligand has been used for the first time for preparation of any coordination complex. A polymeric array of one-dimensional silver-ligand complex is formed where each metal ion is coordinated to two 4-pyridyl groups of two different ligands and two O-atoms of a nitrate ion. Single crystal X-ray data shows presence of hydrogen bonding and π-π stacking between each one-dimensional array which leads to formation of channels in its solid state. The hydrogen bonding interactions have also been verified by Hirsfeld surface analysis plots. Antimicrobial property study of ligand 3,5-bis-(4-pyridyl)-1,2,4-oxadiazole has been performed with Lactobacillus plantarum and it inhibits the growth at 12.5 μg mL-1.