2‐Hydroxyethyl‐Substituted (NHC)Pd(II)PPh3 Complexes: Synthesis, Characterization, Crystal Structure and Its Application on Sonogashira Cross‐Coupling Reactions in Aqueous Media

Abstract

AbstractThis study contains the synthesis of the novel series of the 2‐ hydroxyethyl substituted Pd‐based N‐heterocyclic carbene (NHC) / triphenylphosphine (PPh3) complexes. The (NHC)Pd(II)PPh3 complexes have been prepared from the PPh3 ligand, replaced by 3‐chloro pyridine ligand in (NHC)Pd(II)(3‐Cl‐pyridine) complexes. The novel 2‐hydroxyethyl substituted (NHC)Pd(II)PPh3 complexes have been characterized by using 1H NMR, 13C {1H}NMR, 31P {1H}NMR, FTIR spectroscopy, and elemental analysis techniques. Molecular and crystal structure of 1 f was obtained by using single‐crystal X‐ray diffraction method. The novel 2‐hydroxyethyl substituted (NHC)Pd(II)PPh3 complexes have been examined as catalysts in the Sonogashira cross‐coupling reactions aqueous medium and demonstrated excellent activity in this reaction.