Abstract
We have comprehensively investigated the structure-stability relationship of natural polyphenols in DMEM medium without cells. Polyphenols with catechol or pyrogallol structure were evidently instable in DMEM medium without cells. Herein, we further investigate metabolites of quercetin and luteolin when incubated with several cells (cancer and normal) and its related mechanism. After incubated with SK-28, Caco-2, HepG2, MCF-7, A549, 231, LO2, and LX2 cells at 37 °C in 5% CO2 for 24-72 h, the new products of quercetin and luteolin were found to quite different from different cells. It is time to investigate what really happened for polyphenols and the new products of polyphenols in various cells, as well as the related mechanism. It is very important to further check the bioactivity of these new products, which will avoid erroneous conclusions for what’s the really bioactive compounds.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
