Abstract
Gastric ulcer is one of the disorders that affects a wide proportion of the population and exposes the patient to cancer if the mucosal congestion not treated properly. The pathogenesis of gastric ulceration was explained by many scientists through different experimental animal models. The imbalance between the offensive elements and defensive mechanisms of the stomach play a major role in the incidence of gastric injury. Helicobacter pylori infection, nonsteroidal antiinflammatory drugs (NSAIDs), ethanol addiction, smoking, and stress are considered as detrimental agents that damage the gastric mucosa. Gum Arabic was traditionally used to treat many disorders, including stomach illness. Researchers linked the constituents of gum Arabic and its efficacy in maintaining the normal status of gastric mucosa. The high percentage of polysaccharides in the aqueous solution of gum Arabic may explain its gastroprotective potential against gastritis and be a promising therapy in treating gastric cancer.
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