Abstract
were collected and analysed in a univariate and multivariate model. Results: Hemodynamically compromising rejection occurred in 60 patients for an overall incidence of 10.3%. Death or retransplant at 1 year occurred in 19 patients with HCR (32%). Diabetes, female gender and black race were identified as risk factors for HCR. Univariate analysis identified biventricular failure, hypotension, acute renal failure, the need for inotropic support and low histologic grade biopsy score as variables of clinical importance for predicting death or retransplant at 1 year. Multivariate model identified biventricular failure and inotropic support as two variables of major clinical significance. Conclusions: In the modern era of immunosuppression, rejection with hemodynamic compromise remains a major complication after heart transplantation. Diabetes, female gender and black race represent important risk factors for this complication. Biventricular failure and the need for inotropic support were identified as significant prognostic factors.
Published Version
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