Abstract
A detailed overview of arsenic biosensors and advancements is presented with particular emphasis on recombinant whole-cell-based biosensors using engineered plasmid constructs with the inherent ars operon in cells as the basis of biorecognition. The review discusses the need for the development of rapid, sensitive, and accurate analysis of arsenic because of its widespread toxicity. New approaches for arsenic detection using nanosensor platforms as next-generation biorecognition elements are detailed, suggesting their role in high-throughput detection. Although their use for arsenic biosensing is in its infancy and their precision in onsite detection is yet to be established, the capability of aptamer-graphene nanoensembles to augment conventional detection methods to be considered as reference points of action for risk assessments is proposed.
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