2426 Sliding Sign Testing Could be a Potential Alternative to Laparoscopy to Predict Endometriosis Fertility Index (EFI) in Endometriosis Associated Infertility

Abstract

Study Objective EFI is a robust tool to predict pregnancy rate in endometriosis patients who attempt non-in vitro fertilization conception. However, EFI calculation requires laparoscopy. Sliding sign is a newly established technique that can predict Pouch of Douglas (POD) obliteration with a high degree of accuracy. The objective of this study is to investigate the relationship between sliding sign and the EFI, and to explore the practicality of using sliding sign to predict EFI score less than seven. Design Observational study from a prospective registry (Endometriosis Pelvic Pain Interdisciplinary Cohort (EPPIC), ClinicalTrials.gov#NCT02911090). Analyzed data was captured from December 2013 to June 2017. Setting Tertiary referral center at British Columbia Women's Hospital. Patients or Participants Eighty-six women who are less than 40 years old. Interventions Dynamic ultrasonography for the sliding sign testing and EFI calculation during laparoscopic surgery. Measurements and Main Results Patients with a negative sliding sign(N=26,Group I) were older, had stage IV endometriosis, and a lower median EFI score than patients who had a positive sliding sign (N=60,Group II).Patients in group I had significantly lower surgical factor scores, Regarding the EFI historical factors, group I participants had a longer duration of infertility with no significant difference in parity or age compared to group II. Logistic regression showed that an EFI score Conclusion The sliding sign could be a potential alternative to the EFI surgical factors, and it could be used in combination with EFI historical factors to predict an EFI score