24 IS POOR ADHERENCE TO HYPERTENSIVE TREATMENT ASSOCIATED WITH THE RISK OF OBSTRUCTIVE SLEEP APNEA IN LONG TERM DIALYSIS PATIENTS?

Abstract

Background: Obstructive Sleep Apnea (OSA) is one of the causes of secondary hypertension. Vast majority of secondary hypertensive patients have uncontrolled blood pressure due to poor adherence to treatment. However, the association between adherence to hypertensive treatment and the risk of OSA in long term dialysis patients remains unclear. Objective: This study aimed to investigate the association between adherence to hypertensive treatment and the risk of OSA in long term dialysis patients. Method: A cross-sectional study was conducted on eighty-nine hypertensive patients at the Rasyida Kidney Hospital, Medan, North Sumatera. Adherence to hypertensive treatment was measured using the Morisky Medication Adherence Scale (MMAS) questionnaire while the risk of OSA was assessed utilizing the STOP-Bang questionnaire (a tool used to help diagnose OSA). Patients' age, gender, history of smoking, and body mass index (BMI) were also analyzed as possible associated factors. The Chi-Square test and multivariate analysis were used to analyze the association between study variables. Results: Multivariate analysis showed that older age (>50 years old) and higher BMI (>25 kg/m2) were significantly associated with high risk of OSA (OR=6.449; 95% CI= 2.246-18.520; p=0.001 and OR=6.130; 95% CI= 2.105-17.849; p=0.001, respectively). In contrary, we found no significant association between adherence to hypertensive treatment and the risk of OSA (p=0.679). Conclusion: No association between adherence to hypertensive treatment and the risk of OSA was found in long term dialysis patients. However, being older and having higher BMI were significantly associated with higher risk of OSA in long term dialysis patients.