Abstract
Objectives Hypertensive disorders represent the major cause of maternal morbidity in middle income countries. Chronic hypertension occurs in up to 5% of pregnant women with special challenges to health care providers. Complications depend on the hypertension etiology, duration and severity. Chronic hypertension is a known risk factor for superimposed preeclampsia, with worse maternal-fetal outcomes. Objective: to describe maternal and perinatal outcomes of pregnancies complicated by chronic hypertension followed at the State University of Campina’s high risk outpatient clinic during an 18 months period. Methods Retrospective study with chart review of pregnancies complicated by chronic hypertension at the State University of Campinas (from January/2012 to June/2013). Results 113 women were considered, with mean age of 33 years, mostly white (56%), with partner (82%), multiparous (76%), education over elementary (62%). Mean duration of hypertension was 7 years and most women used anti-hypertensive drugs prior to pregnancy (65%) and were obese (53%). The majority used low dose aspirin and calcium during prenatal care (95%). Over 90% used anti-hypertensive drugs during pregnancy. Mean number of prenatal care visits was 9, with mean referral to high-risk clinic around 16 weeks. The majority of women were evaluated by a cardiologist (83%) with only 3.5% cardiac disease diagnosed. Superimposed preeclampsia occurred in 21% of all cases, with 13% of Intensive Care Unit admissions. Fetal assessment by Doppler velocimetry was systematically performed after 28 weeks of gestation, and only 9 pregnancies (8%) presented fetal distress. Mean gestational age at resolution was 37 weeks and mean fetal weight at birth 2960 g. C-section was performed in 68% of all cases and 58 women underwent postpartum tubal sterilization. Conclusions Pregnancies complicated by chronic hypertension should be referred to high-risk prenatal care assistance. There is increased risk of superimposed preeclampsia and clinical and fetal surveillance are essential to guarantee adequate outcomes. Disclosures M.T. Moreno: None. A.C. Cortez: None. F. Cavichiolli: None. M.A. Parpinelli: None. F.G. Surita: None. M. Costa: None.
Published Version
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