Abstract

RLN and RXFP1 are expressed in the basal plate (BP) and the syncytiotrophoblast of the placenta. RLN is known to cause collagen dissolution and may be involved in trophoblastic invasion. In placenta accreta, the BP is missing which allows the trophoblast (TR) to invade into myometrium. We sought to define the expression of RLN and RXFP1 in normal placental TR and BP throughout gestation and to compare their expression in TR and BP in placenta accretas, with tissues of the same gestational ages.

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