230 A Comparative Study Between Central Quadrantectomy and Nipple Resection with Areola Preservation Versus Grisotti Flap Mammoplasty in Central Breast Lesions Extending to Nipple: A Randomized Clinical Trial

Abstract

Abstract Aim To evaluate central quadrantectomy and nipple resection with areola preservation (CQ-NR-AP) as a new reconstructive oncoplastic technique Versus Grisotti flap mammoplasty (GFM) in central malignant tumours of the breast extending to the nipple, in terms of time procedures, breast symmetry, patient satisfaction, post-operative complications and local recurrence. Method The current study is a single-blind, prospective, randomized, controlled, single-center trial conducted from May 2018 to May 2023 in the breast surgical unit of Ain Shams University Hospitals, which included 40 patients presented with central breast lesions extending to the nipple including one-year follow-up postoperative. Results As regards the mean intra-operative time in minutes, in the group (I) was 80.1 with a standard deviation of ±13.9, and ingroup (II) was 138.9 with a standard deviation of ±14.02(p=0.001). The seroma was detected in zero cases in group (I) and 2(10%) cases in group II (p=0.487) and those two cases were managed by aspiration only. Regarding, the wound infection was found in one case (5%) in group (I) and 3(15%) cases in group II (p=0.605). Regarding patient satisfaction and breast symmetry was much better in the group (I) Conclusions Central quadrantectomy and nipple resection with areola preservation were determined to be safer, easier, and associated with a lower incidence of complications in one-year follow-up as compared to the Grisotti flap mammoplasty technique. In addition, better patient satisfaction is one of the most difficult accomplishments in the management of centrally located breast tumors.