Abstract

Conditions such as congenital anomalies of genitalia, penile cancer, traumatic penile injury and some vasculogenic erectile dysfunctions often require extensive surgical procedures to correct anatomical and functional deformities. The ultimate goal of these procedures is to restore a cosmetically acceptable penis that allows normal urinary, sexual and reproductive function. However, reconstruction of the penis has consistently been a challenge, primarily owing to the shortage of native tissue and inability to restore normal tissue function. In recent years, tissue engineering techniques have been developed to generate biological substitutes that could be used to restore and maintain normal tissue function. This chapter presents various tissue engineering and regenerative medicine approaches that aim to achieve functional penile tissue.

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