Abstract
Atopic dermatitis (AD) and psoriasis (PS) are inflammatory skin diseases and one of the features of AD is dominant colonization with Staphylococcus aureus (S. aureus). Inflammasomes are protein complexes that contribute to host defense against pathogens and cleave the cytokines pro- interleukin (IL)-1β and pro-IL-18 into their secreted active forms. In the current study, we measured the expression of IL-1 family members and inflammasome components in the skin of PS and AD patients and studied their regulation by cytokines, S.
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