Abstract
Background: Antenatal inflammation elicits a fetal inflammatory response which has been suggested causal in acute neonatal and chronic neurological morbidity. Knowledge of temporal changes in levels of proinflammatory and modulatory cytokines during the transition from fetal to neonatal life may improve understanding of the possible relationship between inflammatory response, circulatory impairment and subsequent brain damage in preterm infants. Objective: To evaluate temporal profiles of proinflammatory and modulatory cytokines in fetal and neonatal blood and determine their relationship to arterial hypotension and morphological brain damage in preterm infants.
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