210: Marijuana use in teen pregnancy

Abstract

Substance use and high-risk behavior in teens increases risk of unplanned pregnancy. This study aims to examine demographic factors associated with marijuana use in teen pregnancy, and to determine its effect on pregnancy outcomes in this population. We examined teen pregnancy data from a database known as Peribank that has collected data on over 25,000 pregnancies since August 2011 from one urban county hospital. This is a nested cohort study of pregnant teens (14-19 years old) with a history of marijuana use during pregnancy from 8/2011-6/2017. Marijuana use was identified by self-report and/or urine drug screen. Demographic and perinatal outcomes were compared between Marijuana users and nonusers. All teen pregnancies of study subjects were included. General linear mixed methods were used as needed for analysis of correlated data. Confounders were assessed and controlled for by including them in the regression models. All statistical analysis was done using SAS statistical software (vs 9.4, Cary, NC). 1726 teen pregnancies were included in the analysis. There were 98 marijuana users (5.7%), and 1628 nonusers (94.3%) in the population. Marijuana users were associated with non-Hispanic ethnicity, higher education status, higher weight gain in pregnancy, sexually transmitted infection and mental health diagnosis compared to marijuana nonusers (Table 1). Marijuana users were noted to have a higher rate of tobacco (smoking), e-cigarette, alcohol and polydrug use in pregnancy (Table 1). In univariate analysis, there was a higher rate of congenital anomalies, preeclampsia, post term pregnancy and cesarean delivery among marijuana users (Table 1). After adjusting for race and smoking, marijuana users were noted to have a similar rate of congenital anomalies, preeclampsia, post term pregnancy and sexually transmitted infection (Table 2). Marijuana use in teen pregnancies is less common in Hispanics in an urban setting. Marijuana use is associated with a higher rate of tobacco smoking and polydrug use but is not independently associated with an increased risk of adverse perinatal outcomes. Our data suggest the need for a large, well-powered study to assess the risk for cesarean delivery amongst teen marijuana users.View Large Image Figure ViewerDownload Hi-res image Download (PPT)