Abstract

•Endoscopic ultrasonography-guided biliary drainage (EUS-BD) is now generally preferred over percutaneous methods in patients with biliary obstruction and failed biliary cannulation during endoscopic retrograde cholangiopancreatography (ERCP), and should be considered in those with an inaccessible papilla.•EUS BD is gaining popularity as an alternative for patients with non-resectable malignant hilar strictures and inadequate drainage of the left liver lobe by ERCP.•EUS-guided pancreatic duct drainage is a promising option for pancreatic ductal drainage in patients with symptomatic obstructed pancreatic duct, but should be preserved for selected cases in expert centers.•Advanced techniques, high-level experience in EUS as well as ERCP, and dedicated devices are required for the above procedures to achieve superior efficacy and good safety profile of the procedures.

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