Abstract
Hydroxyapatite (HA) film was prepared on stainless steel (SUS316L) plate using radio-frequency magnetron sputtering, and the as-sputtered films were re-crystallized using a low temperature hydrothermal treatment. Adsorption of albumin on the HA film was measured. The amount of adsorbed albumin on the HA film increased from 55 ± 13mg/m^2 to 104 ± 20mg/m^2 after a 24h-hydrothermal treatment. Release of albumin on the HA film was measured. The amount of released albumin on the HA film increased with incubation time. Contact angle was measured to study the antithrombogenicity. The albumin adsorbed 24h-hydrothermally treated HA film had better hydrophilicity than the non-adsorbed HA film. When the surface shifted a hydrophilicity or hydrophobicity, antithrombogenicity had become better.
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