Abstract
This chapter provides an overview of the changes in structure of mitochondria in situ. Examination of fixed specimens reveals that the mitochondria often have certain structural features characteristic of the cell in which they occur and there is evidence that this structure is not necessarily constant. There are short-term changes of the type revealed by phase contrast microscopy of living cells, and there are long-term changes brought about by changes in the physiological state of the organism, changes in the environment and the diet, and changes because of development, differentiation, and disease. The chapter also presents the structural changes during development and differentiation, structural changes during gametogenesis, structural changes because of changes in diet, and structural changes because of changes in environment and physiological state.
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