Abstract

Microwave-assisted [2+2] cycloaddition of (E)-3-dimethylamino-1-heteroaryl-prop-2-en-1-ones to dimethyl acetylenedicarboxylates gives (2E,3E)-dimethyl-2-[(dimethylamino)methylene]-3-(substituted)succinates in 8–91% yield. In the case of a 4,5-dihydrothiazoline derivative, cycloaddition also took place at the endocyclic CN double bond.

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