Abstract

To reveal mechanism of airflow in alveolus, numerical simulation of airflow considering the expansion and contraction of acinar model was conducted using a realistic pulmonary acinus model. Pulmonary acinar model based on synchrotron micro-CT of mice. Model scale was 893 × 727 × 930 μm^3. The expansion and contraction deforming was changed sinusoidally with time as the moving boundary condition. To evaluate fluid mixing mechanism, streamline was drawn. Consequently, generation and disappearance of the vortex was observed periodically near wall surface of pulmonary acinar model.

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