Abstract
Epidemiologic studies have shown that exposure to traffic-related air pollutants including particulate matter and soot is associated with signs of extrinsic skin aging such as facial pigment spots and wrinkles. In order to study the underlying mechanisms we have developed a standardized, robust ex vivo human skin model which allows application of ambient relevant, toxicologically well characterized, traffic-related diesel exhaust particles (DEP) onto the surface of human skin. By employing this model we previously discovered that topical exposure of human skin to DEP at environmentally relevant nontoxic concentrations increased skin pigmentation.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call