Abstract
To compare automated to manual platelet counts in pregnant women with severe thrombocytopenia through labor, in order to allow them neuraxial blocks. A retrospective cohort study of anesthetic and obstetric data of 385 women in labor with automated platelet counts< 100000μ/L, who were admitted to single referral center during 2013-2018. These automated platelets were compared with manual platelet counts, using standard hematological method. The study group was divided into 3 subgroups according to the severity of the thrombocytopenia as measured by the automated platelets, Group I (75-99000/μL), Group II (50000-74000/μL) and Group III (< 50000/μL) and compared it with the manual counts, respectively. 75000μ/Land 100000 μ/L manual platelet counts were used as a lower cutoff for placing neuraxial blocks. The manual platelet counts were significantly higher than automated count across all study group and subgroups with p< 0.001(table1). Number of women with manual platelet counts of >100000/μL were 70.95% (171/241) in group I, 27.6% (31/112) in group II and 9.38% (3/32) in group III. When we used cutoff of >75000/μL the number of women with manual platelet counts were 96.68%(233/241) in group I, 72.3%(81/112) in group II and 31.25% (10/32) in group III (Figure 1). No women had an epidural or spinal hematoma. Using manual platelet counts allow more women to be with neuraxial blocks.
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