1658 Hormone Replacement Therapy use After Premature Surgical Menopause

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Study Objective Assess hormone replacement therapy (HRT) use in patients undergoing premature surgical menopause, and correlate that with surgical indication for menopause. Design Retrospective cohort study. Setting Academic tertiary care center. Patients or Participants Surgically menopausal patients aged ≤45 years who underwent minimally invasive hysterectomy with salpingo-oophorectomy from September 2012- June 2018. Interventions HRT prescription in the 6 week postoperative period. Measurements and Main Results Sixty-three patients met inclusion criteria. Of those, 52% were prescribed HRT in the 6 week postoperative period. Indications for surgical menopause included pelvic pain/endometriosis (32%), gynecological malignancy (21%), BRCA (18%), breast cancer (10%), Lynch syndrome (4.8%), and other (14%). Forty five percent of BRCA patients, 25% of gynecological malignancy patients and 80% of patients with pelvic pain used HRT postoperatively. In patients who utilized HRT postoperatively, 76% were offered preoperative HRT counseling, compared to 33% of patients who did not start postoperative HRT (p Conclusion In patients who undergo premature surgical menopause, more than half utilized HRT postoperatively. Patients with pelvic pain are more likely to use HRT, whereas those with gynecologic or breast malignancy and genetic susceptibility for malignancy are less likely to use HRT. Preoperative HRT counseling is associated with postoperative HRT use.