Abstract
Background: Several studies have demonstrated that skin pH can play an important role in regulation of enzyme activity primarily in keratinization and barrier function. The skin microbiome is influenced by the condition of the host skin, such as moisture and sebum content, presence of skin antimicrobial peptides, skin pH, etc. It has been previously shown that skin pH increases with skin dryness or when skin is washed with a harsh soap. The skin pH is also shown to be higher in patients with atopic eczema, where there is a dysbiosis in the microbiome balance, in particular the relative abundance of Staphylococcus aureus and Staphylococcus epidermidis.
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