Abstract

Current front-line treatment for NSCLC includes PD1/PDL1 checkpoint inhibitors (CPI) alone or in combination with chemotherapy. Second line treatment approach is an unmet need, mainly limited to Docetaxel, and the utility of CPI is an open question. Here we report preliminary data of cohort 1 of the REPLAY trial that assess the efficacy of pembrolizumab (pembro) re-challenge.

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