Abstract
Publisher Summary This chapter is intended to familiarize the enzymologist with some aspects of the theory of perturbations, particularly with those concepts that also occur in enzyme kinetics. The chapter restricts itself to a purely pedagogical treatment of one step in this methodology, namely the inference of the nuclear magnetic resonance (NMR) relaxation times and chemical shifts that a small molecule has while it is bound to an enzyme. The NMR spectrum of a substrate or inhibitor of an enzyme often shows measurable changes when the enzyme is present. Studies of such perturbations have yielded much information about the properties of the enzyme active site. In addition, the chapter also develops the view that enzymes catalyze nuclear spin relaxation and related processes.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
