Abstract
Background: The importance of a balanced skin microbiome for skin appearance is widely recognized. Acne vulgaris is known to arise from increased sebum and hyperkeratinization which are thought to stimulate Propionibacteria acnes proliferation leading to inflammation. Bacteriophages, bacteria-specific viruses, are natural components of the skin microbiome. P. acnes bacteriophages are more abundant on healthy skin than on acne skin1. BX001, a topical gel containing natural bacteriophages specifically targeting P.
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