1580 IMPACT OF PROSTATE SPECIFIC ANTIGEN, PROSTATIC SIZE AND HISTOPATHOLOGY ON ACUTE URINARY RETENTION

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You have accessJournal of UrologyBenign Prostatic Hyperplasia: Basic Research1 Apr 20111580 IMPACT OF PROSTATE SPECIFIC ANTIGEN, PROSTATIC SIZE AND HISTOPATHOLOGY ON ACUTE URINARY RETENTION Huseyin Cihan Demirel, Cevdet Serkan Gökkaya, Cuneyt Ozden, Binhan Kagan Aktas, Suleyman Bulut, and Ali Memis Huseyin Cihan DemirelHuseyin Cihan Demirel Ankara, Turkey More articles by this author , Cevdet Serkan GökkayaCevdet Serkan Gökkaya Ankara, Turkey More articles by this author , Cuneyt OzdenCuneyt Ozden Ankara, Turkey More articles by this author , Binhan Kagan AktasBinhan Kagan Aktas Ankara, Turkey More articles by this author , Suleyman BulutSuleyman Bulut Ankara, Turkey More articles by this author , and Ali MemisAli Memis Ankara, Turkey More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.02.1616AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The most common cause of obstructive acute urinary retention (AUR) is benign prostatic hyperplasia (BPH). For investigating the aetiology of AUR elaborately, we evaluated the relationship between AUR and its different aetiologic factors such as patient age, prostate specific antigen (PSA) level, prostatic size and histopathology. METHODS Between January and December 2008, two hundred and twenty six patients who underwent transurethral resection of prostate (TURP) procedure due to AUR or lower urinary tract symptoms (LUTS) were included in the study. Patients were classified into two groups; namely AUR and LUTS groups. AUR group consisted of 89 (39.38%) and LUTS group 137 (60.62%) patients. AUR group included the patients in whom catheterization required due to bladder distention for the first time in their lives. Two groups were compared in respect to patient age, prostatic size, histopathology and PSA level for determining the possible impact of AUR on these parameters. Pearson's chi-square and Mann-Whitney U tests were applied and p values under 0.05 were considered as significant. RESULTS The mean age of AUR group was significantly higher than LUTS group (p<0,0001). The mean PSA level of AUR group was higher than LUTS group but that was not significant (p=0,089). The greater the size of prostate, the greater the risk of getting AUR. Thus the mean weight of resected prostatic tissue was higher in AUR group than LUTS group (p=0.031) (Table 1). Table 1. Patient characteristics (mean±SD) (min-max) All patients (n=226) AUR group (n=89) LUTS group (n=137) p value⁎ Age (year) 67,7±7,7(38-84) 70,1±6,1(59-84) 66,1±8,2(38-84) >0,0001 PSA level (ng/ml) 6,45±4,97(0,6-20) 7,6±5,15(0,6-20) 5,54±4,7(0,8-16) 0,089 Weight of resected prostatic tissue (gr) 25,47±21,77(10-135) 29,35±24,58(10-135) 22,95±19,4(10-110) 0,031 SD, standard deviation; PSA, prostate specific antigen; AUR, acute urinary retention; LUTS, lower urinary tract symptoms. ⁎ Comparison between the data of AUR and LUTS groups. The patients were compared as to prostatic histopathology. Histopathology of prostatic specimen was not related to the presence of AUR (p=0.115) (Table 2). There was not any difference between the patients with BPH and prostatitis in terms of mean age, PSA level, weight of resected prostatic tissue. Duration of catheterization was longer in patients with prostatitis histopathology than the ones with BPH. Table 2. Relationship between AUR presence and prostate histopathology. Histopathology AUR (+) AUR (-) Total (n) p value BPH 59(36,2%) 104(63,8%) 163 Prostatitis 30(45,4%) 33(54,6%) 63 0,115⁎ AUR, acute urinary retention; BPH, benign prostatic hyperplasia. ⁎ Comparison between the histopathologic results of AUR (+) and AUR (-) groups. CONCLUSIONS In the present study we have determined that higher age, PSA and prostatic size were risk factors for AUR development while prostatic histopathology (being BPH or prostatitis) was not. © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 185Issue 4SApril 2011Page: e634-e635 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.MetricsAuthor Information Huseyin Cihan Demirel Ankara, Turkey More articles by this author Cevdet Serkan Gökkaya Ankara, Turkey More articles by this author Cuneyt Ozden Ankara, Turkey More articles by this author Binhan Kagan Aktas Ankara, Turkey More articles by this author Suleyman Bulut Ankara, Turkey More articles by this author Ali Memis Ankara, Turkey More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...