Abstract
Background: Several studies have reported on acute skin toxicity outcomes in breast cancer (BC) patients treated with proton therapy (PT). However, limited data is available on (1) acute skin toxicity outcomes of mildly hypofractionated intensity modulated PT, and (2) on PT outcomes of model-based selected BC patients. Therefore, the primary objective of this study was to assess the incidence and severity of acute skin toxicity in these BC patients, and the secondary objectives were to assess predictive factors and dose-effect relationships.
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